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Symbol
Name
ID
Tnfsf14
tumor necrosis factor (ligand) superfamily, member 14
MGI:1355317
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
abnormal osteoclast differentiation
decreased T cell proliferation
increased T cell proliferation
decreased splenocyte proliferation
intestinal inflammation
colitis
small intestinal inflammation
increased spleen weight
spleen hyperplasia
abnormal T cell subpopulation ratio
abnormal gamma-delta T cell morphology
increased IgA level
increased IgG level
abnormal T cell physiology
abnormal cytotoxic T cell physiology
decreased cytotoxic T cell cytolysis
abnormal T cell activation
abnormal complement protein level
abnormal lymph node cell ratio
lymph node hyperplasia
decreased interferon-gamma secretion
decreased interleukin-10 secretion
decreased interleukin-2 secretion
decreased interleukin-4 secretion
decreased tumor necrosis factor secretion
increased autoantibody level
increased anti-nuclear antigen antibody level
increased anti-double stranded DNA antibody level
abnormal inflammatory response
decreased inflammatory response
liver inflammation
myositis
glomerulonephritis
lung inflammation
increased length of allograft survival
Availability Mouse Genotype
Tnfsf14tm1Ddy/Tnfsf14tm1Ddy *
Tnfsf14tm1Kpf/Tnfsf14tm1Kpf
Tnfsf14tm1Lpc/Tnfsf14tm1Lpc *
Tnfsf14tm1Wwh/Tnfsf14tm1Wwh
Tg(Lck-Tnfsf14)24Yxf/?

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory